Hypertriglyceridemia and Acute Pancreatitis
نویسندگان
چکیده
منابع مشابه
Familial hypertriglyceridemia-induced acute necrotizing pancreatitis: A case report
Acutepancreatitis can infrequently be a life-threatening complication of hypertriglyceridemia. Rarely, hypertriglyceridemia can originate from an inborn genetic error in lipoproteins metabolism. This condition can be manifested by very high serum triglyceride levels (>1000 mg/dl) and a more severe and lethal form of pancreatitis. Here, we present a case of acute pancreatic which was found out t...
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Everolimus is an mTOR inhibitor commonly used to treat metastatic pancreatic neuroendocrine tumors (pNETs) and renal cell carcinoma, and for posttransplant immunosuppression. This report presents a case of a 36-year-old man being treated with everolimus for a metastatic pNET who developed severe hypertriglyceridemia and acute pancreatitis. The incidence of hypertriglyceridemia reported in large...
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Acute pancreatitis (AP) is a condition characterised by the activation of the normally inactive digestive enzymes due to an etiological factor and digestion of the pancreatic tissues, resulting in extensive inflammation and leading to local, regional, and systemic complications in the organism. It may vary from the mild edematous to the hemorrhagic and severely necrotising form. The most common...
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Acute pancreatitis and eruptive xanthomas are the only recognised direct complications of severe hypertriglyceridaemia. We present the case of a 33-years old male patient in whom the onset of a type 2 diabetes, added to an unknown familial hyperlipidemia, precipitated a dramatic raise of serum triglyceride levels, that cause in turn an acute pancreatitis and the appearance of dermic eruptive xa...
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The detailed pathophysiological mechanisms involved in the progression of hypertriglyceridemia to pancreatitis are little known. Using an animal model we have found that the earliest detectable changes caused by hypertriglyceridemia consist of a selective degeneration of the mitochondria in the exocrine pancreas cells. This supports the view that an excess of free fatty acids deranges the mitoc...
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ژورنال
عنوان ژورنال: JAMA Internal Medicine
سال: 2013
ISSN: 2168-6106
DOI: 10.1001/2013.jamainternmed.477